pentobarbital decreases levels of ponatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Keep away from Unless of course the coadministration outweighs the doable hazard of ponatinib underexposure; watch for signs of lowered efficacy.
pentobarbital will lessen the level or outcome of disopyramide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.
pentobarbital will minimize the extent or impact of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
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Keep an eye on Carefully (1)pentobarbital will reduce the level or effect of hydrocodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Warning when discontinuing CYP3A4 inducers which might be coadministered with hydrocodone; plasma concentrations of hydrocodone could raise and may lead to most likely deadly respiratory depressionSerious - Use Different (1)hydrocodone, pentobarbital.
pentobarbital will reduce the level or influence of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives can be lessened. Use of a nonhormonal contraceptive is recommended.
pentobarbital will lower the level or impact of estrogens esterified by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will reduce the extent or impact of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
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pentobarbital will reduce the level or result of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the level or result of copyright topical by impacting hepatic enzyme CYP2B6 metabolism. Minimal/Importance Unknown.
pentobarbital will lower the level or influence of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the extent or impact of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.
pentobarbital and olopatadine intranasal both enhance sedation. Stay clear of or Use Alternate Drug. Coadministration increases threat of CNS melancholy, which read more may result in additive impairment of psychomotor overall performance and result in daytime impairment.